Erectile Dysfunction – What We Treat

Erectile Dysfunction

ERECTILE FUNCTION AND ERECTILE DYSFUNCTION (ED)

How Does My Penis Get Big and Hard?

An erection occurs when the spongy erectile tissue in the penis fills with blood. The usual way this occurs in the body is via the “Nitric Oxide – Cyclic GMP Pathway”

Learn How It Works

  • Various sexual stimuli (emotional, imaginative, visual, tactile, auditory, olfactory, etc) are received by the body and relayed to an area deep within the brain called the limbic system.
  • Depending on the nature and extent of the stimuli, brain cells in the limbic system can become “excited” and send electrical signals into the spinal cord and eventually out to the penis via parasympathetic nerves to tell it to become erect.
  • These nerves terminate at the single cell layer (endothelium) lining the inside of arteries which supply blood to the erectile tissue.
  • There are three storage cylinders filled with spongy tissue (the paired corpora cavernosa and the single corpus spongiosum) which along with the urethra constitute the entirety of what’s inside the penis.
  • The nerve signals cause the endothelial cells to make and release nitric oxide (NO).
  • The NO diffuses into the network of smooth muscle cells which comprise the middle layer of the arterial wall.
  • Inside of the muscle cells, NO activates an enzyme (guanylate cyclase) which transforms GTP (guanasine triphosphate) molecules into cGMP (cyclic guanasine monophophate) molecules.
  • cGMP is the chemical that causes the smooth muscle cells to relax.
  • cGMP is broken down fairly quickly by another enzyme called phosphodiesterase (PDE), but as long as nerve signals continue to arrive and cause release of NO and activation of guanylate cyclase, more cGMP is made.
  • If enough cGMP is produced to relax the muscle layer sufficiently, the arterial wall expands outward and the opening (lumen) in the artery widens and more blood can flow through it.
  • The arterial blood vessels carry the blood into “storage spaces” (sinusoids) inside of the spongy tissue.
  • The increased blood flow allows the sinusoids to fill up and expand.
  • Collagen and elastic fibers (tunica albuginea) like the “casing of a sausage” enclose the corpora and gives rigidity to the penis when they are stretched by the increased blood volume in the sinusoids. On average, a 3-fold increase in blood volume is needed to obtain a functional erection.
  • But, like when trying to fill up a bathtub, there needs to be a way to plug the drainage system. Unlike arteries, veins don’t have a thick muscular layer that can contract and limit flow.
  • The tiny, thin-walled veins that drain blood from the sinusoids come together to form a plexus of veins located between the peripheral sinusoids and the tunica albuginea before passing through the tunica on their way out of the penis.
  • When the sinusoids expand and the tunica is stretched tight, the venous plexus and exiting veins are compressed.
  • There is a marked reduction of blood leaving the corpora, blood volume in the corpora increases and the penis becomes increasingly firm. Pretty darn amazing!
  • After ejaculation occurs or the limbic brain loses interest, parasympathetic nerve signals to the corpora stop and the Nitric Oxide – Cyclic GMP Pathway shuts down.
  • The smooth muscle cells in the erectile tissue vasculature then return to their usual moderate state of contraction under the control of the sympathetic nervous system.
  • Blood flow and trapping is decreased and the erect penis returns to its flaccid state.

ED: Why Are My Erections Getting Weaker?

Like your car, the performance of your penis declines over time. You’re driving a penis that came off the assembly line sometime during the last century! The engine parts of your vehicle are old and getting older every year.

Unlike your car, your stuck with it. You can’t buy or lease a new one. The degenerative changes occurring in the arteries of your penis especially can lead to ED. “Hardening of the Arteries” (arteriosclerosis) is when cholesterol plaque is deposited in the arterial walls, making them stiff and harder to open completely.

This means less blood can flow into the spongy erectile tissue and it gradually becomes more and more difficult to achieve and maintain an erection firm enough to sustain sexual intercourse.

85% of ED cases are primarily due to arteriosclerosis and we call this Vasculogenic ED. The other 15% of ED cases are:

  • Hormonal ED
  • Psychological ED
  • Medication Induced ED
  • Alcohol/Drug Related ED
  • Neurologic ED
  • Surgery/Radiation Related ED
  • Traumatic ED
  • BPH Associated ED

Frequently, ED is due to a
combination of factors.

Arteriosclerosis happens to everyone to some extent over time, but some people are affected sooner and to a greater extent.

  • Hereditary is very important but unfortunately can’t be changed.
  • Lifestyle is important and can be modified.
  • High blood pressure, high cholesterol, diabetes, smoking, obesity, lack of exercise, kidney disease, etc., all accelerate arteriosclerosis and can be treated.

If you have a history of previous heart attack, stroke, bypass surgery, angioplasty or stent placement, you have already shown that you have arteriosclerotic disease elsewhere and the arteries in your penis are almost certainly affected as well.

TREATMENT OPTIONS:
  • REGENERATIVE MEDICINE
  • ORAL ED MEDICATION
  • INJECTABLE MEDICATION
ERECTILE DYSFUNCTION (ED)

We are the specialists. Our board certified physician can determine and explain why this is happening. At the Men’s Clinic in Charleston, we offer the most complete array of treatments.

Call today to schedule a consultation guaranteed to provide you with answers and effective options.

READ REAL REVIEWS. THE RESULTS DO THE TALKING.

– Andrew M.

“I have been a customer for almost two years and have only praise for their services, which have certainly helped me and my wife. The reception staff is first class, as of course is the Doctors.”

- Andrew M.

– Gary S.

“The personnel at Men’s Clinic are professional and friendly. I never feel uneasy or intimidated during my visits. I feel that having an all men staff promotes the relaxed atmosphere at the clinic. I’m looking forward to a better lifestyle. Thanks!”

- Gary S.

– Benjamin R.

“I surely can say from the first day I received my first visit with the Doctor, everything went just fine for me. My problem was treated, and I am satisfied. I was taken care of by good professionals in the office.”

- Benjamin R.

Roy A.

“Professional, Competent, and expert analysis. Took the necessary time to explain and educate this patient on the specifics of care. Subject matter expert physician.”

Roy A.

Thomas R.

“Was excited with the results of the first test run and was thinking how marvelous it is. Unfortunately, we found that the arteries in the penis were likely in too poor condition to help. (I should have had more frequent sex either with a partner or by myself)”

Thomas R.

Dan B.

“I felt the people were professional and the setup of the office makes you feel your being treated discreetly. The most important thing is that the treatment works.”

Dan B.

Timonthy B.

“The entire team extends a professional and compassionate approach to those hoping to find a solution to this unfortunate condition.”

Timonthy B.

Joseph B.

“This clinic is rock solid. Great group and great results.”

Joseph B.

Scott A.

“Very friendly and knowledgeable staff.”

Scott A.

Bruce B.

“Very professional and attentive to my needs and expectations. Always courteous”

Bruce B.

Richard H.

“Works perfect for me, much better than Viagra!”

Richard H.

Todd W.

“I think the Mens Clinic is the best thing that ever happened to me.”

Todd W.

Gene K.

“This is a GREAT place and their products work.”

Gene K.

Carl N.

“Caring service. Jeremy wants do to the right thing.”

Carl N.

Jeff W.

“Great initial visit, very educational.”

Jeff W.